DMASC
The Data Management, Auditing, and Statistical Center for the Cancer Prevention Clinical Trials Network (CP‑CTNet)
About CP-CTNet
The Cancer Prevention Clinical Trials Network (CP-CTNet) is a major program of the National Cancer Institute (NCI) Division of Cancer Prevention (DCP). The purpose of CP-CTNet is to perform and provide clinical trial support for the efficient conduct of early-phase clinical trials, evaluate the biologic effects of preventive agents and interventions, and determine clinically relevant correlates in order to advance their development for cancer prevention.
The key components of CP-CTNet are the CP-CTNet sites and the CP-CTNet Data Management, Auditing, and Statistical Center (DMASC). Each CP-CTNet site consists of a Lead Academic Organization (LAO) and Affiliated Organizations (AOs) that work together to perform cancer prevention clinical trials.
About DMASC
The Data Management, Auditing, and Statistical Center coordinates cross-network activities for centralized data management and reporting, clinical trials auditing, statistics, and administrative coordination across CP-CTNet Sites. In addition, DMASC collaborates with, and advises, CP-CTNet Sites with respect to trial design and protocol development.
DMASC is led by Jens Eickhoff, PhD, of the University of Wisconsin (Multiple Principal Investigator) and Sue Siminski, MS, MBA, of Frontier Science Foundation (Multiple Principal Investigator).
Interactive Map of the Cancer Prevention Clinical Trials Network (CP-CTNET)
⬤ DMASC
⬤ DCP
⬤ Lead Academic Organizations (LAOs)
⬤ Affiliated Organizations (AOs) – Active
⬤ Affiliated Organizations (AOs)
What the DMASC Does
Data Management and Reporting
- Centralized data collection system via Medidata Rave®
- 24/7 user support
- Written data management quality procedures
- Site training, reporting of data and metrics
Clinical Trials Auditing
- Independent auditing of trials and processes
- Guidance to ensure GCP, regulatory, and NCI guidelines are followed
- Collaboration with Site staff to identify systemic improvements
Administration and Coordination
- Unified operational structure
- Procedural documentation
- Biospecimen inventory
Statistics
- Statistical consultation and expertise for all CP-CTNet clinical trials
- Primary statisticians of record for all cross-network clinical trials
- Statistical support to CP-CTNet Sites
Lead Academic Organizations
Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Northwestern Cancer Prevention Consortium
University of Arizona, University of Arizona Cancer Prevention Clinical Trials Network (UA CP-CTNet)
University of Texas MD Anderson Cancer Center, iCAN-PREVENT: International Cancer Prevention Clinical Trial Consortium
University of Michigan, Early Phase Clinical Cancer Prevention Consortium (ClinCaP)
The University of Wisconsin, The MW Chemoprevention Network