Active Trials

Title Status DCP ID
An Extended Follow-up Study of the HPV Vaccine Delayed Booster Trial
University of Arizona
DCP-ApprovedUAZ20-01-02
Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD)
Northwestern University
DCP-ApprovedNWU20-01-03
A Randomized and Placebo-Controlled Phase II Trial Targeting Dominant-Negative Missense Mutant p53 by Atorvastatin for Reducing the Risk of Longstanding Ulcerative Colitis-Associated Cancer
Northwestern University
DCP-ApprovedNWU20-02-02
Surgical Window of Opportunity Study of Megesterol Acetate and Metformin for Endometrial Intraepithelial Neoplasia
Northwestern University
DCP-ApprovedNWU20-02-01
Clinical Study of Bioactivity of Low Dose Apalutamide in Prostate Cancer Patients Scheduled for Prostatectomy
University of Arizona
DCP-ApprovedUAZ20-01-01
A Phase IIa, Placebo-Controlled, Randomized Study of Daily Obeticholic Acid (OCA) to Reduce Intestinal Polyp Burden in Familial Adenomatous Polyposis (FAP)
M.D. Anderson Cancer Center
DCP-ApprovedMDA20-01-01
Time Restricted Eating and Metformin (TEAM) in Breast Cancer (BC) and Adjacent Intraepithelial Neoplasia (IEN). A Randomized, Phase IIb, Window of Opportunity PreSurgical Trial
M.D. Anderson Cancer Center
DCP-ApprovedMDA20-02-01
A Phase II Trial of the Immunogenicity of a DNA Plasmid Based Vaccine (STEMVAC) Encoding Th1 Selective Epitopes from Five Antigens Associated with Breast Cancer Stem Cells (MDM2, YB1, SOX2, CDC25B, CD105) in Patients with Early Stage Triple Negative Breast Cancer
University of Wisconsin
DCP-ApprovedUWI20-00-01
Metformin for Chemoprevention of Lung Cancer in High Risk Obese Patients
Northwestern University
DCP-ApprovedNWU20-04-01
Obeticholic Acid for Chemoprevention in Barrett’s Esophagus
University of Michigan Rogel Cancer Center
DCP-ApprovedUMI21-05-01
A Phase II Clinical Trial of the Multitargeted Recombinant Adenovirus 5 (CEA/MUC1/Brachyury) Vaccine (Tri-Ad5) in Lynch syndrome
Northwestern University
DCP-ApprovedINT21-05-01
A Dose Escalation Phase I Trial of the Safety and Immunogenicity of RG1-VLP, A Candidate Broadly Protective Vaccine for the Prevention of HPV-Associated Cancer
University of Wisconsin
DCP-ApprovedUWI20-04-01
Pilot Study of GCC Agonists to Identify A Cyclic-GMP Signal in Duodenal Tissue of Healthy Volunteers
University of Wisconsin
DCP-ApprovedUWI21-06-01
Phase II Randomized, Placebo-Controlled Trial of Broccoli Seed and Sprout Extract (BSSE) to Evaluate Sustained Detoxication of Tobacco Carcinogens in Heavy Smokers (BSSE)
University of Arizona
DCP-ApprovedUAZ21-06-01
A Phase Ib Clinical Trial of Nous-209 for Recurrent Neoantigen Immunogenicity and Cancer Immune Interception in Lynch Syndrome Patients
M.D. Anderson Cancer Center
DCP-ApprovedMDA21-06-01
M4OC-Prevent 2.0: Phase IIb Trial of Metformin for Oral Cancer Prevention
University of Arizona
DCP-ApprovedUAZ21-07-01
A Phase II Trial of Oral Iloprost for the Precision Chemoprevention of Lung Cancer
Northwestern University
DCP-ApprovedNWU21-08-01
ONC201 for Chemoprevention in Colorectal Cancer (BrUOG 399)
University of Michigan Rogel Cancer Center
DCP-ApprovedUMI22-09-02
Randomized Trial of Apalutamide in Non-Muscle Invasive Bladder Cancer
University of Wisconsin
DCP-ApprovedINT22-09-01
Phase IIA Trial of Acolbifene (20 mg) vs Low Dose Tamoxifen (5 mg) in Pre-menopausal Women at High Risk for Development of Breast Cancer
University of Michigan Rogel Cancer Center
DCP-ApprovedUMI22-09-01
Calcipotriol plus 5-fluorouracil Immunotherapy for Skin Cancer Prevention in Organ Transplant Recipients
University of Arizona
DCP-ApprovedUAZ22-10-01
Randomized, Placebo-Controlled Trial of Broccoli Seed and Sprout Extract (BSSE) to Evaluate Detoxification of Carcinogens in Firefighters
University of Arizona
DCP-ApprovedUAZ22-11-01
A Phase II Placebo-Controlled Trial of Urolithin A Supplementation In Men With Prostate Cancer Undergoing Radical Prostatectomy
Northwestern University
DCP-ApprovedNWU22-12-01
A Phase 0 Trial of Omeprazole and Low Dose Aspirin to Identify Pharmacodynamic Biomarkers of Preventive Efficacy in the Colon
University of Michigan Rogel Cancer Center
DCP-ApprovedUMI23-13-01
Refining Tamoxifen Dose for Premenopausal Breast Cancer Prevention (RENAISSANCE): A Phase II Single Arm Trial
Northwestern University
DCP-ApprovedINT23-14-01
Phase 2 Study of Low Dose Tamoxifen +/-High Dose EPA & DHA Omega-3 Fatty Acids in Obese Postmenopausal Women at Increased Risk for Breast Cancer
University of Michigan Rogel Cancer Center
DCP-ApprovedUMI23-14-02
Phase 1a Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)
University of Michigan Rogel Cancer Center
DCP-ApprovedUMI23-15-01
Phase 2 Study to Evaluate the Safety and Efficacy of TPST-1495 in Patients with Familial Adenomatous Polyposis (FAP)
University of Wisconsin
DCP-ApprovedUWI23-16-01
Repurposing Itraconazole for Secondary Prevention of Metaplasia and Primary Prevention of Cancer in Patients with High-risk Barrett’s Esophagus after Ablation
University of Michigan Rogel Cancer Center
DCP-ApprovedUMI23-16-01
Evaluating the Feasibility of a Survivin Peptide Vaccine (SurVaxM) as an Interception Agent in Patients at High Risk for Lung Cancer
Northwestern University
DCP-ApprovedNWU24-19-01

DCP-Approved Trials

Title Status DCP ID
GLP-1 Receptor Agonist in Combination with Progestin Intrauterine Device for Treatment of Endometrial Hyperplasia and Grade 1 Endometrioid Endometrial Cancer in Overweight and Obese Women
M.D. Anderson Cancer Center
DCP-ApprovedMDA24-19-01
A Phase II Randomized Trial of Checkpoint Inhibition for the Regression of Airway Dysplasia in High-Risk Current and Former Smokers with or without a History of Early-Stage Lung Cancer
Northwestern University
DCP-ApprovedNWU25-21-01
A Phase II Hepatocellular Carcinoma (HCC) Prevention Trial of Two Different Doses of Osimertinib in Patients with Non-Alcoholic Steatohepatitis
Northwestern University
DCP-ApprovedNWU25-23-02