{"id":11,"date":"2025-09-15T13:47:57","date_gmt":"2025-09-15T13:47:57","guid":{"rendered":"https:\/\/www.fsf-dev.org\/public\/?page_id=11"},"modified":"2025-09-24T12:51:08","modified_gmt":"2025-09-24T12:51:08","slug":"trials","status":"publish","type":"page","link":"https:\/\/www.fsf-dev.org\/public\/trials\/","title":{"rendered":"Trials"},"content":{"rendered":"\n
\n

Trials<\/h2><\/div>\n<\/div>\n\n\n\n
\n

Active Trials<\/h2>\n\n\n
\r\n \r\n \r\n \r\n \r\n
Title<\/th>\r\n Status<\/th>\r\n DCP ID<\/th>\r\n <\/tr>\r\n <\/thead>\r\n
An Extended Follow-up Study of the HPV Vaccine Delayed Booster Trial<\/div>
University of Arizona<\/div><\/td>
DCP-Approved<\/td>UAZ20-01-02<\/td><\/tr>
Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD)<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU20-01-03<\/td><\/tr>
A Randomized and Placebo-Controlled Phase II Trial Targeting Dominant-Negative Missense Mutant p53 by Atorvastatin for Reducing the Risk of Longstanding Ulcerative Colitis-Associated Cancer<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU20-02-02<\/td><\/tr>
Surgical Window of Opportunity Study of Megesterol Acetate and Metformin for Endometrial Intraepithelial Neoplasia<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU20-02-01<\/td><\/tr>
Clinical Study of Bioactivity of Low Dose Apalutamide in Prostate Cancer Patients Scheduled for Prostatectomy<\/div>
University of Arizona<\/div><\/td>
DCP-Approved<\/td>UAZ20-01-01<\/td><\/tr>
A Phase IIa, Placebo-Controlled, Randomized Study of Daily Obeticholic Acid (OCA) to Reduce Intestinal Polyp Burden in Familial Adenomatous Polyposis (FAP)<\/div>
M.D. Anderson Cancer Center<\/div><\/td>
DCP-Approved<\/td>MDA20-01-01<\/td><\/tr>
Time Restricted Eating and Metformin (TEAM) in Breast Cancer (BC) and Adjacent Intraepithelial Neoplasia (IEN). A Randomized, Phase IIb, Window of Opportunity PreSurgical Trial<\/div>
M.D. Anderson Cancer Center<\/div><\/td>
DCP-Approved<\/td>MDA20-02-01<\/td><\/tr>
A Phase II Trial of the Immunogenicity of a DNA Plasmid Based Vaccine (STEMVAC) Encoding Th1 Selective Epitopes from Five Antigens Associated with Breast Cancer Stem Cells (MDM2, YB1, SOX2, CDC25B, CD105) in Patients with Early Stage Triple Negative Breast Cancer<\/div>
University of Wisconsin<\/div><\/td>
DCP-Approved<\/td>UWI20-00-01<\/td><\/tr>
Metformin for Chemoprevention of Lung Cancer in High Risk Obese Patients<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU20-04-01<\/td><\/tr>
Obeticholic Acid for Chemoprevention in Barrett’s Esophagus<\/div>
University of Michigan Rogel Cancer Center<\/div><\/td>
DCP-Approved<\/td>UMI21-05-01<\/td><\/tr>
A Phase II Clinical Trial of the Multitargeted Recombinant Adenovirus 5 (CEA\/MUC1\/Brachyury) Vaccine (Tri-Ad5) in Lynch syndrome<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>INT21-05-01<\/td><\/tr>
A Dose Escalation Phase I Trial of the Safety and Immunogenicity of RG1-VLP, A Candidate Broadly Protective Vaccine for the Prevention of HPV-Associated Cancer<\/div>
University of Wisconsin<\/div><\/td>
DCP-Approved<\/td>UWI20-04-01<\/td><\/tr>
Pilot Study of GCC Agonists to Identify A Cyclic-GMP Signal in Duodenal Tissue of Healthy Volunteers<\/div>
University of Wisconsin<\/div><\/td>
DCP-Approved<\/td>UWI21-06-01<\/td><\/tr>
Phase II Randomized, Placebo-Controlled Trial of Broccoli Seed and Sprout Extract (BSSE) to Evaluate Sustained Detoxication of Tobacco Carcinogens in Heavy Smokers (BSSE)<\/div>
University of Arizona<\/div><\/td>
DCP-Approved<\/td>UAZ21-06-01<\/td><\/tr>
A Phase Ib Clinical Trial of Nous-209 for Recurrent Neoantigen Immunogenicity and Cancer Immune Interception in Lynch Syndrome Patients<\/div>
M.D. Anderson Cancer Center<\/div><\/td>
DCP-Approved<\/td>MDA21-06-01<\/td><\/tr>
M4OC-Prevent 2.0: Phase IIb Trial of Metformin for Oral Cancer Prevention<\/div>
University of Arizona<\/div><\/td>
DCP-Approved<\/td>UAZ21-07-01<\/td><\/tr>
A Phase II Trial of Oral Iloprost for the Precision Chemoprevention of Lung Cancer<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU21-08-01<\/td><\/tr>
ONC201 for Chemoprevention in Colorectal Cancer (BrUOG 399)<\/div>
University of Michigan Rogel Cancer Center<\/div><\/td>
DCP-Approved<\/td>UMI22-09-02<\/td><\/tr>
Randomized Trial of Apalutamide in Non-Muscle Invasive Bladder Cancer<\/div>
University of Wisconsin<\/div><\/td>
DCP-Approved<\/td>INT22-09-01<\/td><\/tr>
Phase IIA Trial of Acolbifene (20 mg) vs Low Dose Tamoxifen (5 mg) in Pre-menopausal Women at High Risk for Development of Breast Cancer<\/div>
University of Michigan Rogel Cancer Center<\/div><\/td>
DCP-Approved<\/td>UMI22-09-01<\/td><\/tr>
Calcipotriol plus 5-fluorouracil Immunotherapy for Skin Cancer Prevention in Organ Transplant Recipients<\/div>
University of Arizona<\/div><\/td>
DCP-Approved<\/td>UAZ22-10-01<\/td><\/tr>
Randomized, Placebo-Controlled Trial of Broccoli Seed and Sprout Extract (BSSE) to Evaluate Detoxification of Carcinogens in Firefighters<\/div>
University of Arizona<\/div><\/td>
DCP-Approved<\/td>UAZ22-11-01<\/td><\/tr>
A Phase II Placebo-Controlled Trial of Urolithin A Supplementation In Men With Prostate Cancer Undergoing Radical Prostatectomy<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU22-12-01<\/td><\/tr>
A Phase 0 Trial of Omeprazole and Low Dose Aspirin to Identify Pharmacodynamic Biomarkers of Preventive Efficacy in the Colon<\/div>
University of Michigan Rogel Cancer Center<\/div><\/td>
DCP-Approved<\/td>UMI23-13-01<\/td><\/tr>
Refining Tamoxifen Dose for Premenopausal Breast Cancer Prevention (RENAISSANCE): A Phase II Single Arm Trial<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>INT23-14-01<\/td><\/tr>
Phase 2 Study of Low Dose Tamoxifen +\/-High Dose EPA & DHA Omega-3 Fatty Acids in Obese Postmenopausal Women at Increased Risk for Breast Cancer<\/div>
University of Michigan Rogel Cancer Center<\/div><\/td>
DCP-Approved<\/td>UMI23-14-02<\/td><\/tr>
Phase 1a Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)<\/div>
University of Michigan Rogel Cancer Center<\/div><\/td>
DCP-Approved<\/td>UMI23-15-01<\/td><\/tr>
Phase 2 Study to Evaluate the Safety and Efficacy of TPST-1495 in Patients with Familial Adenomatous Polyposis (FAP)<\/div>
University of Wisconsin<\/div><\/td>
DCP-Approved<\/td>UWI23-16-01<\/td><\/tr>
Repurposing Itraconazole for Secondary Prevention of Metaplasia and Primary Prevention of Cancer in Patients with High-risk Barrett’s Esophagus after Ablation<\/div>
University of Michigan Rogel Cancer Center<\/div><\/td>
DCP-Approved<\/td>UMI23-16-01<\/td><\/tr>
Evaluating the Feasibility of a Survivin Peptide Vaccine (SurVaxM) as an Interception Agent in Patients at High Risk for Lung Cancer<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU24-19-01<\/td><\/tr> <\/tbody>\r\n <\/table>\r\n<\/div>\n\n\n

DCP-Approved Trials<\/h2>\n\n\n
\r\n \r\n \r\n \r\n \r\n
Title<\/th>\r\n Status<\/th>\r\n DCP ID<\/th>\r\n <\/tr>\r\n <\/thead>\r\n
GLP-1 Receptor Agonist in Combination with Progestin Intrauterine Device for Treatment of Endometrial Hyperplasia and Grade 1 Endometrioid Endometrial Cancer in Overweight and Obese Women<\/div>
M.D. Anderson Cancer Center<\/div><\/td>
DCP-Approved<\/td>MDA24-19-01<\/td><\/tr>
A Phase II Randomized Trial of Checkpoint Inhibition for the Regression of Airway Dysplasia in High-Risk Current and Former Smokers with or without a History of Early-Stage Lung Cancer<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU25-21-01<\/td><\/tr>
A Phase II Hepatocellular Carcinoma (HCC) Prevention Trial of Two Different Doses of Osimertinib in Patients with Non-Alcoholic Steatohepatitis<\/div>
Northwestern University<\/div><\/td>
DCP-Approved<\/td>NWU25-23-02<\/td><\/tr> <\/tbody>\r\n <\/table>\r\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

Active Trials DCP-Approved Trials<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":9,"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":831,"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/pages\/11\/revisions\/831"}],"wp:attachment":[{"href":"https:\/\/www.fsf-dev.org\/public\/wp-json\/wp\/v2\/media?parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}